GeneCE-100 offers nucleic acid quality control for a range of applications, including DNA QC, NGS libraries, cell-free DNA (cfDNA), PCR fragments and RNA QC. lt provides consistent high-precision analysis by using the same single-channel cartridge. And it provides flexible sample capacity from 1 to 104 samples.
Experimental Process
Features
1 Convenient Operation
Equipped with a 10-inch rotatable touch screen as standard, which can switch between horizontal and vertical screens according to analysis needs.
2 Cartridge Precast Gel
No need for manual glue preparation and filling, just plug and play, Each cartridge can analyze 240 samples.
3 Parallel Analysis
A single test throughput of 1-104 samples can be achieved.
4 High Sensitivity
Nucleic acids can be detected at concentrations as low as 0.2pg/µL.
5 High Resolution
For DNA fragments within 500bp, the resolution can reach 1-4bp, and for fragments within 200bp, the resolution can reach 1bp.
6 Cartridge Life Counting
The RFID chip embedded in the cartridge can auto-record the number of tests and the expiration date, and give a prompt.
7 Reliable Results
Provides sample concentration, fragment length, 28S/18S, genomic DNA integrity DII value, RNA integrity RII value, etc.
8 Various Specifications
Including DNA-related high-sensitivity, high-resolution, large-fragment and standard kits, RNA-related high-sensitivity and standard kits.
Fragment Analysis Kit
4 fragment analysis kits are suitable for the GeneCE-100 biological fragment analysis system, mainly used for the detection of DNA fragment size and concentration of samples such as gDNA, cfDNA, FFPE blocks, PCR products, fragmentation libraries, etc. Compared with traditional electrophoresis, it has the advantages of high resolution, fast separation speed, low sample consumption, high detection sensitivity and fully automated.
DNA Fragment Analysis Kit | ||||
Name | Standard (DNA) cartridge kit (SC2) | High resolution (DNA) cartridge kit (SH1) | High sensitivity (DNA) cartridge kit (NH1) | Large fragment (DNA) cartridge kit (LS1) |
Separation Range | 20-5000bp | 20-5000bp | 20-5000bp | 20-23000bp |
Maximum Resolution | 4-10bp | 1-4bp | 4-10bp | 4-10bp |
Number of Cartridge | 240 times | 240 times | 100 times | 240 times |
LOD | 1pg/uL | 1pg/uL | 0.2pg/uL | 20pg/μL |
Application | NGS library quality control, PCR detection | Multiplex PCR detection, SSR analysis | Analysis of low-concentration DNA samples, such as cfDNA | Genome, next-generation sequencing library |
Common Applications
Genomic DNA Quality Control
Performs initial sample QC on gDNA samples, evaluates samples for degradation, and ensures integrity of initial samples.
Library Quality Control
By high-precision detection of the fragment distribution and fragment size for NGS libraries, it ensures that the library quality meets the sequencing requirements, thus enhancing the reliability of sequencing data and experimental efficiency.
cfDNA Quality Control
Conduct quality control on cfDNA samples to determine whether there is contamination of high molecular weight genomic DNA. Determine the degree of cfDNA degradation through fragment peak shape to ensure the reliability of downstream applications.
PCR Product Analysis
High resolution (DNA) cartridge kit (SH1) can significantly improve the resolution of multi-target detection and is suitable for applications such as SNP, SSR, multiplex PCR, and bacterial/viral screening and identification.
The field of biological fragment analyzers has long been dominated by overseas brands, and GeneCE-100 is one of the few products in China with independent intellectual property rights. If GeneCE-100 is paired with the Allsheng Auto-NGS series automated NGS library preparation workstation, it can make your NGS library preparation process more complete.